Ah receptor represses acute-phase response gene expression without binding to its cognate response element
نویسندگان
چکیده
منابع مشابه
Ah Receptor Binding to its Cognate Response Element is Required for Dioxin-Mediated Toxicity
The aryl hydrocarbon receptor (AHR) is a ligand-activated member of the bHLH-PAS family of transcription factors. Members of this family include HIF1a, EPAS, and SIM, which are involved in hypoxia and nervous system development. Another member of this family, aryl hydrocarbon nuclear translocator (ARNT), is the dimerization partner for the AHR. The AHR is often classified as a sensor of a wide ...
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ژورنال
عنوان ژورنال: Laboratory Investigation
سال: 2009
ISSN: 0023-6837,1530-0307
DOI: 10.1038/labinvest.2009.24